What is CBD?

Cannabidiol, more commonly known as CBD, is a non-psychoactive compound regularly found in the cannabis plant and more recently found in a variety of Asian hops [1]. It is just one of the 80+ phytocannabinoids the cannabis plants produce, Tetrahydrocannabinol (THC) being the most known compound due to its psychoactive effects (CBD counteracts the effects of THC). As more people have been looking to CBD as a natural and safer alternative to their ailments, it has allowed for more modern research to be conducted. The Chinese have been using cannabis as medicine since as early as 2800 BCE. CBD is known for its anti-inflammatory, antioxidant, and anti-anxiety properties [2]. It is commonly used for joint pain, insomnia, and depression. A CBD based medicine, Epidiolex is currently being used to help those who suffer from two rare and severe forms of epilepsy [3]. CBD is proving to be a very versatile compound.

Chemical make up of CBD.

How does it work?

In 1992 the first endogenous cannabinoid receptor was discovered in the brain. As years went on, they started to discover more cannabinoid receptors and their ligands throughout the nervous, digestive, immune system and major organs in what became a new body system known as the endocannabinoid system (ECS). CBD interacts with endocannabinoid receptors, known as CB1 and CB2, throughout the body to modulate and regulate important internal functions. The most abundant receptors are found in the brain, making CBD a key component in helping with various mental issues and neuroprotection in numerous neurodegenerative disorders [4]. The ECS is also responsible for sleep, pain, inflammation, memory, and appetite. A deficient endocannabinoid system is believed to be the root cause of several internal issues. What is now the theory of Clinical Endocannabinoid Deficiency (CECD) states that a deficiency in the endocannabinoid system can lead to irritable bowel syndrome, migraines, and fibromyalgia [5]. CBD equalizes a deficient endocannabinoid system and promotes homeostasis providing many health benefits.

CBD Infographic | Hemp Extract Health Benefits

Is CBD Legal?

The short answer is YES. The long answer is you have to know the difference between the different types of Cannabis Sativa and where the CBD was derived from. There’s marijuana, which is slang for a plant with high THC content, and there’s hemp, which is known for its very low THC content. According to the 2018 Farm Bill, hemp with at or less than 0.3% THC is removed from the Controlled Substance Act [6]. The World Anti-doping Agency removed CBD from its banned substance list allowing Olympic and MMA athletes to benefit from the plant.

Cannabis leaf and judge gavel

Can you overdose od CBD?

No, it would be very hard to overdose from CBD, the lethal dose of CBD is considered to be roughly 115mg per lb of body weight consumed over a short period of time. You should also know that CBD is a stool softener so taking too much of it might have some unwanted results.

Are there any side effects?

There are very few known side effects to CBD but the most common are diarrhea, changes in appetite, and fatigue.